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1

Relation Between Polymorphic Transformation Pathway During Grinding and the Physicochemical Properties of Bulk Powders for Pharmaceutical Preparations

Otsuka, Makoto, Otsuka, Kuniko, Kaneniwa, Nobuyoshi

Journal:

Drug Development and Industrial Pharmacy

Year:

1994

Language:

english

File:

PDF, 409 KB

english, 1994

2

Effect of seed crystals on solid-state transformation of polymorphs of chloramphenicol palmitate during grinding1

Makoto Otsuka, Nobuyoshi Kaneniwa

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 672 KB

english, 1986

3

Application of the Pidgeon-Pitlick method for calculation of the absorption rate constant of drugs whose disposition can be described by the two-compartment open model

Nobuyoshi, Kaneniwa, Tomoo, Funaki, Shigeru, Furuta, Nobutoshi, Watari

Journal:

International Journal of Pharmaceutics

Year:

1986

Language:

english

File:

PDF, 935 KB

english, 1986

4

Effect of lipid solubility on hepatic first-pass metabolism of barbiturates in rabbits

Mitsuru, Hiura, Shinji, Nakagawa, Hisako, Kawashima, Nobuyoshi, Kaneniwa

Journal:

International Journal of Pharmaceutics

Year:

1984

Language:

english

File:

PDF, 919 KB

english, 1984

5

Effects of Temperature and Pressure During Compression on Polymorphic Transformation and Crushing Strength of Chlorpropamide Tablets

MATSUMOTO, TAKAHIRO, KANENIWA, NOBUYOSHI, HIGUCHI, SHIGESADA, OTSUKA, MAKOTO

Journal:

Journal of Pharmacy and Pharmacology

Year:

1991

Language:

english

File:

PDF, 421 KB

english, 1991

6

Spectroscopic Studies on Molecular Interactions. III. Improvement of the Benesi-Hildebrand Method for the Determination of Equilibrium Constants

MORIGUCHI, IKUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1969

File:

PDF, 418 KB

1969

7

Hygroscopicity of Carbamazepine Crystalline Powders

KANENIWA, NOBUYOSHI, YAMAGUCHI, TETSUO, WATARI, NOBUTOSHI, OTSUKA, MAKOTO

Journal:

YAKUGAKU ZASSHI

Year:

1984

File:

PDF, 649 KB

1984

8

Bioavailability and Dissolution Test of Commercial Carbamazepine Tablets

KANENIWA, NOBUYOSHI, UMEZAWA, OSAMU, WATARI, NOBUTOSHI, KAWAKAMI, KATSUMI, ASAMI, HIROKO, SUMI, MASAHIRO

Journal:

YAKUGAKU ZASSHI

Year:

1984

File:

PDF, 780 KB

1984

9

Fluorescence assay of nitrofurantoin with o-aminothiophenol in plasma and urine

Nobutoshi Watari, Tomoo Funaki, Nobuyoshi Kaneniwa

Journal:

Journal of Pharmaceutical Sciences

Year:

1980

Language:

english

File:

PDF, 212 KB

english, 1980

10

Dose- and time-dependent kinetics of the renal excretion of nitrofurantoin in the rabbit

Nobutoshi Watari, Kazumasa Aizawa, Nobuyoshi Kaneniwa

Journal:

Journal of Pharmaceutical Sciences

Year:

1985

Language:

english

File:

PDF, 741 KB

english, 1985

11

Effect of geometric factors on hydration kinetics of theophylline anhydrate tablets

Makoto Otsuka, Nobuyoshi Kaneniwa, Kuniko Otsuka, Katsumi Kawakami, Osamu Umezawa, Yoshihisa Matsuda

Journal:

Journal of Pharmaceutical Sciences

Year:

1992

Language:

english

File:

PDF, 436 KB

english, 1992

12

Effect of compression temperature on the consolidation mechanism of chlorpropamide polymorphs

Makoto Otsuka, Takahiro Matsumoto, Shigesada Higuchi, Kuniko Otsuka, Nobuyoshi Kaneniwa

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 519 KB

english, 1995

13

High-performance liquid chromatographic determination of cimetidine in rat plasma, urine and bile

Nobuyoshi Kaneniwa, Tomoo Funaki, Shigeru Furuta, Nobutoshi Watari

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1986

Language:

english

File:

PDF, 259 KB

english, 1986

14

Pharmacokinetic study of the fate of acetaminophen and its conjugates in rats

Nobutoshi Watari, Masuaki Iwai, Nobuyoshi Kaneniwa

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1983

Language:

english

File:

PDF, 1.43 MB

english, 1983

15

Prediction of hepatic first-pass metabolism and plasma levels following intravenous and oral administration of barbiturates in the rabbit based on quantitative structure—Pharmacokinetic relationships

Nobutoshi Watari, Yuichi Sugiyama, Nobuyoshi Kaneniwa, Mituru Hiura

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1988

Language:

english

File:

PDF, 1.05 MB

english, 1988

16

Nonlinear assessment of nitrofurantoin bioavailability in rabbits

Nobutoshi Watari, Tomoo Funaki, Kazumasa Aizawa, Nobuyoshi Kaneniwa

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1983

Language:

english

File:

PDF, 900 KB

english, 1983

17

Estimation of the absorption rate constant for a drug subject to non-linear elimination: Comparison on non-linear regression and the Cmax, Tmax approach

Kaneniwa Nobuyoshi, Funaki Tomoo, Hiura Mitsuru

Journal:

International Journal of Pharmaceutics

Year:

1986

Language:

english

File:

PDF, 524 KB

english, 1986

18

Effect of grinding on the crystallinity and chemical stability in the solid state of cephalothin sodium

Makoto, Otsuka, Nobuyoshi, Kaneniwa

Journal:

International Journal of Pharmaceutics

Year:

1990

Language:

english

File:

PDF, 689 KB

english, 1990

19

Isomerization of Lactose in Solid-state by Mechanical Stress During Grinding

OTSUKA, MAKOTO, OHTANI, HIRO, KANENIWA, NOBUYOSHI, HIGUCHI, SHIGESADA

Journal:

Journal of Pharmacy and Pharmacology

Year:

1991

Language:

english

File:

PDF, 468 KB

english, 1991

20

Comparison of in vivo dissolution of sulfa drugs calculated by deconvolution to absorption rates calculated by multicompartment model method

Nobutoshi, Watari, Nobuyoshi, Kaneniwa, Manabu, Hanano

Journal:

International Journal of Pharmaceutics

Year:

1980

Language:

english

File:

PDF, 726 KB

english, 1980

21

Discontinuous absorption property of cimetidine

Tomoo, Funaki, Sigeru, Furuta, Nobuyoshi, Kaneniwa

Journal:

International Journal of Pharmaceutics

Year:

1986

Language:

english

File:

PDF, 471 KB

english, 1986

22

Analysis of the absorption characteristics of cimetidine with the use of the multi-segment absorption model

Funaki, Tomoo, Watari, Nobutoshi, Furuta, Shigeru, Kaneniwa, Nobuyoshi

Journal:

International Journal of Pharmaceutics

Year:

1988

Language:

english

File:

PDF, 609 KB

english, 1988

23

Dissolution of slightly soluble drugs VII. In vivo drug dissolution in human subjects and rabbits

Nobutoshi, Watari, Nobuyoshi, Kaneniwa

Journal:

International Journal of Pharmaceutics

Year:

1981

Language:

english

File:

PDF, 900 KB

english, 1981

24

Use of fluorescence HPLC for determining extrarenal creatinine clearance in rats

Kaneniwa, Nobuyoshi, Watari, Nobutoshi, Funaki, Tomoo

Journal:

International Journal of Pharmaceutics

Year:

1987

Language:

english

File:

PDF, 990 KB

english, 1987

25

Hepatic first-pass metabolism of hexobarbital in rabbits and dogs

Mitsuru, Hiura, Hisako, Kawashima, Nobuyoshi, Kaneniwa

Journal:

International Journal of Pharmaceutics

Year:

1984

Language:

english

File:

PDF, 502 KB

english, 1984

26

A flip-flop model for nitrofurantoin disposition in the rabbit following oral administration

Nobutoshi, Watari, Tomoo, Funaki, Kazumasa, Aizawa, Nobuyoshi, Kaneniwa

Journal:

International Journal of Pharmaceutics

Year:

1984

Language:

english

File:

PDF, 1.17 MB

english, 1984

27

Effect of Surface Characteristics of Theophylline Anhydrate Powder on Hygroscopic Stability

OTSUKA, MAKOTO, KANENIWA, NOBUYOSHI, KAWAKAMI, KATSUMI, UMEZAWA, OSAMU

Journal:

Journal of Pharmacy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 649 KB

english, 1990

28

Effect of Environment on Crystallinity and Chemical Stability in Solid-State of Ground Cephalotin Sodium During Storage

Otsuka, Makoto, Kaneniwa, Nobuyoshi

Journal:

Drug Development and Industrial Pharmacy

Year:

1991

Language:

english

File:

PDF, 355 KB

english, 1991

29

Effects of the Mechanical Energy of Multi-tableting Compression on the Polymorphic Transformations of Chlorpropamide

Otsuka, Makoto, Matsumoto, Takahiro, Kaneniwa, Nobuyoshi

Journal:

Journal of Pharmacy and Pharmacology

Year:

1989

Language:

english

File:

PDF, 359 KB

english, 1989

30

Correction to: “Dose- and Time-Dependent Kinetics of the Renal Excretion of Nitrofurantoin in the Rabbit”

Watari, Nobutoshi, Aizawa, Kazumasa, Kaneniwa, Nobuyoshi

Journal:

Journal of Pharmaceutical Sciences

Year:

1985

Language:

english

File:

PDF, 111 KB

english, 1985

31

Pharmacokinetic study of carbamazepine and its epoxide metabolite in humans.

SUMI, MASAHIRO, WATARI, NOBUTOSHI, UMEZAWA, OSAMU, KANENIWA, NOBUYOSHI

Journal:

Journal of Pharmacobio-Dynamics

Year:

1987

File:

PDF, 1.09 MB

1987

32

Comparison of disposition parameters of quinidine and quinine in the rat.

WATARI, Nobutoshi, WAKAMATSU, Akira, KANENIWA, Nobuyoshi

Journal:

Journal of Pharmacobio-Dynamics

Year:

1989

File:

PDF, 845 KB

1989

33

Effect of metoclopramide on the absorption of cimetidine in rats.

FUNAKI, TOMOO, FURUTA, SHIGERU, KANENIWA, NOBUYOSHI

Journal:

Journal of Pharmacobio-Dynamics

Year:

1986

File:

PDF, 791 KB

1986

34

Influence of Particle Size on Physicochemical Properties of Pharmaceutical Powders. II. On Packing of Sodium Borate and Boric Acid Powders.

Ikekawa, Akiko, Aoki, Haruko, Masukawa, Kikuya, Kaneniwa, Nobuyoshi

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1967

File:

PDF, 615 KB

1967

35

Influence of Particle Size on Physicochemical Properties of Pharmaceutical Powders. VII. Fluidity and Packing Property of Binary Mixtures

IKEKAWA, AKIKO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1968

File:

PDF, 1.08 MB

1968

36

Influence of Particle Size on Physicochemical Properties of Pharmaceutical Powders. IV. On Packing of Pharmaceutical Powders. (2)

IKEKAWA, AKIKO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1968

File:

PDF, 613 KB

1968

37

Spectroscopic Studies on Molecular Interactions. II. Complexation between Polyvinylpyrrolidone and Iodine

MORIGUCHI, IKUO, ARAKI, YOSHIE, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1969

File:

PDF, 530 KB

1969

38

Influence of Particle Size on Physicochemical Properties of Pharmaceutical Powders. IX. Fluidity of Binary Mixtures of Potato Starch

IKEKAWA, AKIKO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1969

File:

PDF, 734 KB

1969

39

Spectroscopic Studies on Molecular Interactions. VI. Mechanism of Metachromasy of 2-(4'-Hydroxyphenylazo) benzoic Acid by Serum Albumin

MORIGUCHI, IKUO, FUSHIMI, SHIZUO, OHSHIMA, CHIEKO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1970

File:

PDF, 673 KB

1970

40

Adsorption of Solute from the Solutions. IV. Adsorption of Benzoic Acids on Graphite

MORIGUCHI, IKUO, FUSHIMI, SHIZUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1970

File:

PDF, 460 KB

1970

41

Adsorption of Solute from the Solutions. II. Competitive Adsorption of Cyanocobalamin with Pyridoxine and Thiamine on Talc

MORIGUCHI, IKUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1969

File:

PDF, 480 KB

1969

42

Influence of Physicochemical Properties on Ball-Milling of Pharmaceutical Powders

IKEKAWA, AKIKO, IMAGAWA, KANJI, OMORI, TOSHIE, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1971

Language:

english

File:

PDF, 869 KB

english, 1971

43

Adsorption of Solute from the Solutions. III. Repression of Adsorption of Cyanocobalamin on Talc by Polyvinylpyrrolidone

MORIGUCHI, IKUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1969

File:

PDF, 501 KB

1969

44

Spectroscopic Studies on Molecular Interactions. IV. Charge-Transfer Properties and Antibacterial Activity of Sulfonamides

MORIGUCHI, IKUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1969

File:

PDF, 502 KB

1969

45

Adsorption of Solute from the Solutions. V. Adsorption Rate of Cyanocobalamin on Talc

MORIGUCHI, IKUO, FUSHIMI, SHIZUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1970

File:

PDF, 320 KB

1970

46

Spectroscopic Studies on Molecular Interactions. V. Charge-Transfer Property and Enzymatic Acetylation of Aniline Derivatives

MORIGUCHI, IKUO, FUSHIMI, SHIZUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1970

File:

PDF, 533 KB

1970

47

Solvent Effects on π-π Charge-Transfer Complexations

MORIGUCHI, IKUO, FUSHIMI, SHIZUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1971

File:

PDF, 611 KB

1971

48

Influence of Ball-Milling Atmosphere on Decrease of Molecular Weight of Polyvinylpyrrolidone Powders

KANENIWA, NOBUYOSHI, IKEKAWA, AKIKO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1972

File:

PDF, 728 KB

1972

49

Spectral Changes of Various Dyes by Bovine Serum Albumin and by Organic Solvents

MORIGUCHI, IKUO, FUSHIMI, SHIZUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1971

Language:

english

File:

PDF, 561 KB

english, 1971

50

Effect of Water on Rate of Charge-Transfer Reaction of Aniline with Chloranil

MORIGUCHI, IKUO, FUSHIMI, SHIZUO, KANENIWA, NOBUYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1972

Language:

english

File:

PDF, 431 KB

english, 1972